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Below is the uncorrected Black gay escort Nesoddtangen text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. The vast majority are benign and many are beneficial, yet everyone can name microbes that cause disease.

In general, the impact of exposure to a particular microbe depends on the balance of three factors: The outcome of a host-microbe interaction de- pends on multiple factors: Adapted from Swanson et al.

American Society for Microbiology, Copyright ; adapted with permission. No further reproduction or distribution is permitted without the prior written permission of the American Society for Microbiology. First, microbes need to encounter a susceptible host. For Legionella, aerosols of contaminated water or soil can disperse these bacteria, exposing people in the vicinity.

Second, the microbe has to en- ter the host.

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Third, to initiate an infection, microbes must breach inborn defensive barriers. Finally, to cause disease, the infecting microbe needs to in- flict damage. The trauma may be direct, such as when a bacterial toxin punctures host cells, or an indirect effect of a hyperactive inflammatory response, for example.

How the interplay among host defenses, Legionella pneumophila biology, and the ecology of engineered water systems alter the balance between health and disease is the focus of this chapter. However, since its discovery in the s, more than 61 species and 3 subspecies of Legionella have been described, half of which have been isolated from patients e. In people with weakened immune systems, Prostitutes west Drammen other than L.

In Oceania and parts of Asia, disease due to L.

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Human and financial burdens due to Legionella are substantial. Population figures are estimates by Countrymeters countrymeters.

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Most culture-based sys- tems are optimized for L.

For patients with al- tered George Leirvik dating, the sensitivity and the specificity of seroconversion to non-pneumophila Legionella spp.

Kunst, M. Chaloner, J. However, they respond to antibiotic classes and agents that primarily target intracellular infections Sharma et al.

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